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Cat-scratch disease (CSD) is a benign, self-limited zoonotic infection characterized by a primary skin or conjunctival lesion after cat scratches or contact with a cat and subsequent acute to subacute tender regional lymphadenopathy, as well as systemic symptoms that may be debilitating.

Cat-scratch disease is not a severe illness in people who are healthy. But it can be a problem in people with weak immune systems. People with weak immune systems include those who are receiving chemotherapy for cancer, those who have diabetes or those who have acquired immunodeficiency syndrome (AIDS).



Causes:

B.henselae causes granulomatous inflammation in healthy individuals (CSD) and angiogenesis in immuncompromised persons.



Symptoms:

* Bump (papule) or blister (pustule) at site of injury, usually the first sign.
* Swelling of the lymph nodes near where the skin was bitten or scratched.
* Body rash
* Flu-like symptoms including headache, lethargy, decreased appetite, fatigue, joint pain, or fever

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