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Mammary Paget disease is an uncommon skin cancer characterised by a chronic eczema-like rash of the nipple and adjacent areolar skin. It is also called Paget disease of the nipple.

Mammary Paget disease is most commonly diagnosed between 50 and 60 years of age. It is much more common in women than in men.

Mammary Paget disease is associated with an underlying cancer, either in situ adenocarcinoma of the breast or a more widespread infiltrating cancer, although this is sometimes difficult to detect on clinical examination or by mammogram.

A similar condition that involves the skin of female and male genitalia is known as extramammary Paget disease.


Most patients go to their doctor complaining of an itchy, burning rash on and around the nipple area. Sometimes the skin may be broken and sore from itching. Other symptoms include:

* Redness
* Swelling
* Oozing nipple discharge
* Scaling
* Bloody nipple discharge
* Ulceration
* Inversion of the nipple

Scaly, crusty and thickened plaques often form on the nipple, which then spreads to the surrounding area. Usually only one nipple is affected although rare cases of involvement of both nipples has been seen.

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