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Morphoea (US spelling is morphea) is an uncommon persistent condition in which there are areas of thickened skin, and occasionally underlying tissues including bone. It is also known as localised scleroderma. It may affect adults or children, and is at least twice as common in females as males. It is more common in people with white skin compared to darker skin types.

It is important to distinguish morphoea from systemic sclerosis, a multiorgan systemic disease in which there is also hardening of the skin. Unlike systemic sclerosis, morphoea does not result in spindled fingers (sclerodactyly), Raynaud phenomenon or nailfold capillary changes.

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